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CVE-2025-12921

Estado: AnalizadaBaja (2.1)—

A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the public and may be used. The vendor was contacted early about this disclosure but did not respond in any way.

CVSS

Probabilidad de explotación (EPSS)

EPSS (Exploit Prediction Scoring System, de FIRST) estima la probabilidad de que una vulnerabilidad sea explotada en 30 días. Complementa a CVSS (impacto) y a CISA KEV (explotación confirmada).

Tecnologías afectadas (1)

Openclinica — Openclinica

CWE

Referencias

JSON original (NVD)

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{
  "id": "CVE-2025-12921",
  "cveTags": [],
  "metrics": {
    "ssvcV203": [
      {
        "source": "134c704f-9b21-4f2e-91b3-4a467353bcc0",
        "ssvcData": {
          "id": "CVE-2025-12921",
          "role": "CISA Coordinator",
          "options": [
            {
              "exploitation": "poc"
            },
            {
              "automatable": "no"
            },
            {
              "technicalImpact": "partial"
            }
          ],
          "version": "2.0.3",
          "timestamp": "2025-11-14T17:43:08.957976Z"
        }
      }
    ],
    "cvssMetricV2": [
      {
        "type": "Secondary",
        "source": "cna@vuldb.com",
        "cvssData": {
          "version": "2.0",
          "baseScore": 4,
          "accessVector": "NETWORK",
          "vectorString": "AV:N/AC:L/Au:S/C:P/I:N/A:N",
          "authentication": "SINGLE",
          "integrityImpact": "NONE",
          "accessComplexity": "LOW",
          "availabilityImpact": "NONE",
          "confidentialityImpact": "PARTIAL"
        },
        "acInsufInfo": false,
        "impactScore": 2.9,
        "baseSeverity": "MEDIUM",
        "obtainAllPrivilege": false,
        "exploitabilityScore": 8,
        "obtainUserPrivilege": false,
        "obtainOtherPrivilege": false,
        "userInteractionRequired": false
      }
    ],
    "cvssMetricV31": [
      {
        "type": "Secondary",
        "source": "cna@vuldb.com",
        "cvssData": {
          "scope": "UNCHANGED",
          "version": "3.1",
          "baseScore": 4.3,
          "attackVector": "NETWORK",
          "baseSeverity": "MEDIUM",
          "vectorString": "CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:U/C:L/I:N/A:N",
          "integrityImpact": "NONE",
          "userInteraction": "NONE",
          "attackComplexity": "LOW",
          "availabilityImpact": "NONE",
          "privilegesRequired": "LOW",
          "confidentialityImpact": "LOW"
        },
        "impactScore": 1.4,
        "exploitabilityScore": 2.8
      },
      {
        "type": "Primary",
        "source": "nvd@nist.gov",
        "cvssData": {
          "scope": "UNCHANGED",
          "version": "3.1",
          "baseScore": 8.8,
          "attackVector": "NETWORK",
          "baseSeverity": "HIGH",
          "vectorString": "CVSS:3.1/AV:N/AC:L/PR:L/UI:N/S:U/C:H/I:H/A:H",
          "integrityImpact": "HIGH",
          "userInteraction": "NONE",
          "attackComplexity": "LOW",
          "availabilityImpact": "HIGH",
          "privilegesRequired": "LOW",
          "confidentialityImpact": "HIGH"
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        "exploitabilityScore": 2.8
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    ],
    "cvssMetricV40": [
      {
        "type": "Secondary",
        "source": "cna@vuldb.com",
        "cvssData": {
          "Safety": "NOT_DEFINED",
          "version": "4.0",
          "Recovery": "NOT_DEFINED",
          "baseScore": 2.1,
          "Automatable": "NOT_DEFINED",
          "attackVector": "NETWORK",
          "baseSeverity": "LOW",
          "valueDensity": "NOT_DEFINED",
          "vectorString": "CVSS:4.0/AV:N/AC:L/AT:N/PR:L/UI:N/VC:L/VI:N/VA:N/SC:N/SI:N/SA:N/E:P/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/MVI:X/MVA:X/MSC:X/MSI:X/MSA:X/S:X/AU:X/R:X/V:X/RE:X/U:X",
          "exploitMaturity": "PROOF_OF_CONCEPT",
          "providerUrgency": "NOT_DEFINED",
          "userInteraction": "NONE",
          "attackComplexity": "LOW",
          "attackRequirements": "NONE",
          "privilegesRequired": "LOW",
          "subIntegrityImpact": "NONE",
          "vulnIntegrityImpact": "NONE",
          "integrityRequirement": "NOT_DEFINED",
          "modifiedAttackVector": "NOT_DEFINED",
          "subAvailabilityImpact": "NONE",
          "vulnAvailabilityImpact": "NONE",
          "availabilityRequirement": "NOT_DEFINED",
          "modifiedUserInteraction": "NOT_DEFINED",
          "modifiedAttackComplexity": "NOT_DEFINED",
          "subConfidentialityImpact": "NONE",
          "vulnConfidentialityImpact": "LOW",
          "confidentialityRequirement": "NOT_DEFINED",
          "modifiedAttackRequirements": "NOT_DEFINED",
          "modifiedPrivilegesRequired": "NOT_DEFINED",
          "modifiedSubIntegrityImpact": "NOT_DEFINED",
          "modifiedVulnIntegrityImpact": "NOT_DEFINED",
          "vulnerabilityResponseEffort": "NOT_DEFINED",
          "modifiedSubAvailabilityImpact": "NOT_DEFINED",
          "modifiedVulnAvailabilityImpact": "NOT_DEFINED",
          "modifiedSubConfidentialityImpact": "NOT_DEFINED",
          "modifiedVulnConfidentialityImpact": "NOT_DEFINED"
        }
      }
    ]
  },
  "affected": [
    {
      "source": "cna@vuldb.com",
      "affectedData": [
        {
          "vendor": "OpenClinica",
          "modules": [
            "CRF Data Import"
          ],
          "product": "Community Edition",
          "versions": [
            {
              "status": "affected",
              "version": "3.0"
            },
            {
              "status": "affected",
              "version": "3.1"
            },
            {
              "status": "affected",
              "version": "3.2"
            },
            {
              "status": "affected",
              "version": "3.3"
            },
            {
              "status": "affected",
              "version": "3.4"
            },
            {
              "status": "affected",
              "version": "3.5"
            },
            {
              "status": "affected",
              "version": "3.6"
            },
            {
              "status": "affected",
              "version": "3.7"
            },
            {
              "status": "affected",
              "version": "3.8"
            },
            {
              "status": "affected",
              "version": "3.9"
            },
            {
              "status": "affected",
              "version": "3.10"
            },
            {
              "status": "affected",
              "version": "3.11"
            },
            {
              "status": "affected",
              "version": "3.12"
            },
            {
              "status": "affected",
              "version": "3.12.0"
            },
            {
              "status": "affected",
              "version": "3.12.1"
            },
            {
              "status": "affected",
              "version": "3.12.2"
            },
            {
              "status": "affected",
              "version": "3.13"
            }
          ]
        }
      ]
    }
  ],
  "published": "2025-11-10T00:15:44.943",
  "references": [
    {
      "url": "https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md",
      "tags": [
        "Exploit",
        "Third Party Advisory"
      ],
      "source": "cna@vuldb.com"
    },
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      "url": "https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md#poc",
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    },
    {
      "url": "https://vuldb.com/?ctiid.331641",
      "tags": [
        "Permissions Required",
        "VDB Entry"
      ],
      "source": "cna@vuldb.com"
    },
    {
      "url": "https://vuldb.com/?id.331641",
      "tags": [
        "Third Party Advisory",
        "VDB Entry"
      ],
      "source": "cna@vuldb.com"
    },
    {
      "url": "https://vuldb.com/?submit.680872",
      "tags": [
        "Third Party Advisory",
        "VDB Entry"
      ],
      "source": "cna@vuldb.com"
    },
    {
      "url": "https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md",
      "tags": [
        "Exploit",
        "Third Party Advisory"
      ],
      "source": "134c704f-9b21-4f2e-91b3-4a467353bcc0"
    },
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      "url": "https://github.com/mikecole-mg/security_findings/blob/main/openclinica/openclinica-xxe.md#poc",
      "tags": [
        "Exploit",
        "Third Party Advisory"
      ],
      "source": "134c704f-9b21-4f2e-91b3-4a467353bcc0"
    }
  ],
  "vulnStatus": "Analyzed",
  "weaknesses": [
    {
      "type": "Secondary",
      "source": "cna@vuldb.com",
      "description": [
        {
          "lang": "en",
          "value": "CWE-74"
        },
        {
          "lang": "en",
          "value": "CWE-91"
        }
      ]
    },
    {
      "type": "Primary",
      "source": "nvd@nist.gov",
      "description": [
        {
          "lang": "en",
          "value": "CWE-91"
        }
      ]
    }
  ],
  "descriptions": [
    {
      "lang": "en",
      "value": "A vulnerability has been found in OpenClinica Community Edition up to 3.12.2/3.13. Affected by this issue is some unknown functionality of the file /ImportCRFData?action=confirm of the component CRF Data Import. Such manipulation of the argument xml_file leads to xml injection. It is possible to launch the attack remotely. The exploit has been disclosed to the public and may be used. The vendor was contacted early about this disclosure but did not respond in any way."
    }
  ],
  "lastModified": "2026-06-17T08:33:12.823",
  "configurations": [
    {
      "nodes": [
        {
          "negate": false,
          "cpeMatch": [
            {
              "criteria": "cpe:2.3:a:openclinica:openclinica:3.12.2:*:*:*:community:*:*:*",
              "vulnerable": true,
              "matchCriteriaId": "EE82ACB7-759A-4C0F-95B9-396F2BE160A6"
            },
            {
              "criteria": "cpe:2.3:a:openclinica:openclinica:3.13:*:*:*:community:*:*:*",
              "vulnerable": true,
              "matchCriteriaId": "290F6C64-EAB4-488F-BFF0-77B0682BD1CF"
            }
          ],
          "operator": "OR"
        }
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    }
  ],
  "sourceIdentifier": "cna@vuldb.com"
}